How Spravato Can Help When Depression Doesn’t Go Away

For those living with depression—such as major depression disorder (MDD) or treatment-resistant depression (TRD)—traditional treatments don’t always provide the relief they need. Spravato® offers a different approach, working differently to bring new hope for lasting relief.

How Spravato Works

Spravato is a nasal spray form of esketamine, a medication that works very differently from standard antidepressants. Most depression medicines focus on brain chemicals like serotonin. Spravato targets glutamate, which plays a major role in how brain cells communicate. By improving those connections, it may help “reset” mood pathways in the brain.

Relief That Can Happen Sooner

The most exciting difference? Speed. While traditional antidepressants can take weeks to help, Spravato can begin working within 24 hours. Some patients feel lighter, more hopeful, and more motivated after their very first session.

Safe, Guided Treatment in Our Clinic

Treatment is done in our clinic so we can make sure you’re safe and supported. You’ll take the nasal spray under the guidance of our trained team, then relax in a comfortable space for about two hours while we monitor you. Common side effects, like mild dizziness or feeling detached, usually fade quickly.

Is Spravato Right for Me?

Spravato isn’t for everyone. It’s approved for adults with depression that hasn’t improved with at least two other antidepressants. But for the right patient, it can be life-changing — offering a chance to finally break free from the heavy weight of depression.

Take the First Step Toward Relief

If you’ve been struggling without relief, you don’t have to lose hope. Spravato could be the new path forward. Contact Andala Health or fill out our form below to see if this treatment is right for you.